Tuesday, February 18, 2020

Experience in writing Essay Example | Topics and Well Written Essays - 500 words

Experience in writing - Essay Example One of my strongest points is that I have a good command of grammatical correctness; I have always practiced this in the course of improving my communication. In any piece of writing, I give much attention to avoiding spelling and typographical errors that may distort my message. The ability to organize my points in an effective way also forms part of my strengths in writing. To that end, I always ensure that my points are well organized and logically supporting my thesis. However, I have weakness in language use especially in the scenario where I have to choose the right word, among many words leading in the same direction. I tend to confuse the difference between these types of words and may end up using the least-fitting one. My experience also features love and hate stories for writing. What I love most is the ability to communicate my mind without necessarily expressing feelings. I have weakness in expressing true feelings and, thus far, this has made writing a better place since it gives me an ample time for constructing my views to best fit the feeling I intend. In which case, my narrative skills have served me best in improving my confidence and love for writing. Despite the love, I have a strong hate for the rules restricting the use of First-persons pronouns. I always feel that such kind of cases restrict me from fully expressing myself within a piece of writing especially in a case where I would like to identify personally with my narration and let the reader have a glimpse of genuineness.

Monday, February 3, 2020

Curcumin to cure Cancer Research Paper Example | Topics and Well Written Essays - 500 words

Curcumin to cure Cancer - Research Paper Example ies have been performed that hold up curcumin-mediated regulation of COX pathways, which is an essential mechanism by which curcumin stops a number of ailment processes, including the cancer. The precise regulation of COX-2 by curcumin is not fully established; though, existing evidence show that curcumin controls COX-2 mainly at the transcriptional level and, to some extent, the posttranslational level. The curcumin-selective transcriptional control action of the COX-2 inhibitory potential of this naturally occurring agent offer unique advantages over synthetic COX inhibitors, such as non-steroidal anti-inflammatory drugs. Cells will be treated with free Cisplatin and then with free curcumin to test the effectiveness of the chemotherapeutic drug. This control will be compared to a plate of cells treated with nano-encapsulated curcumin along with cisplatin. My hypothesis is that the nanoparticle delivery of drugs will show less resistance in the cells to the chemopreventive drug, a down regulation of COX-2, as well as decreased proliferation. I will be using fluorescent mesoporous  silica  nanoparticles to encapsulate the cisplatin and deliver it to the mitochondria of the cells. The delivery system should not only demonstrate enhanced cellular uptake, but also show an elevated  drug effect which should reduce the associated side effects. In addition, a new, simple and reasonably priced fluorescent based PT quantification technique has been adopted as an alternative of the commonly used ICP-based quantification method and this strategy of quantification could be elaborated to monitor fluorescentà ‚  pro drug  nanoparticles  during real-time diagnosis. A common problem with the present chemotherapeutic interventions is that it causes inflammation in the gut and kidney cells. To test my method against this, I will also conjugate the cisplatin nanoparticles with curcumin to test if the side effects are even further diminished. To measure the effectiveness of the